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Healthcare · Early-Stage Breast-Cancer Nodule Detection

World Health Organization (Freelance Research Grant)

Role: ML Research Lead (Freelance, Research Grant)MedTech · Computer Vision · Oncology ResearchPrior experience — Michele Sanna, research grantStatus: Completed

Multi-view 3D CNN (adapted MedNeXt) over 420,000 mammograms and 38,000 DBT volumes across 11 countries, with a temporal "prior-exam" branch detecting subtle inter-exam changes. DINOv2-style self-supervised pre-training; federated training across hospitals that could not share raw imagery.

  • PyTorch
  • MONAI
  • DICOM/NIfTI
  • cuCIM
  • Weights & Biases
  • Flower (federated)
0.94 AUCdetection on held-out multi-centre test set
41%of lesions later diagnosed at 12–24 months surfaced on prior-negative exams
−28%false positives at matched sensitivity vs. previous best open benchmark (Mirai-class)
WHO guidanceinformed peer-reviewed publication on AI-assisted screening in LMIC contexts

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